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2026

  1. Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema

    W. Xiao, Y. Zhu, X. Tang, K. Zhu, W. Zhang, M. Chen, K. Cai, S. Xu, Z. Wu, M. Wang, J. Liu, L. Long, Z. Tan, A. Wu, S. Zhou, Z. Zhao, Y. Tang, Y. Huang, B. Wang, F. Liu, Q. Wang, F. Yang, D. Jian, W. Shi, H. Xie, X. Chen, L. Guo, Z. Deng, J. Sun, and J. Li
  2. Single-cell transcriptomics reveals hair growth retardation mediated by aberrant connective tissue sheath contraction in male androgenetic alopecia

    G. Li, L. Yang, S. Duan, M. Chen, Y. Zhang, F. Liu, Y. Wang, J. Li, S. Xu, Z. Wu, M. Wang, B. Wang, Z. Zhao, W. Shi, M. Lei, H. Xie, Y. Tang, Z. Deng, and J. Li
    Nature communications. 2026. doi:10.1038/s41467-026-70153-4
  3. Real-world experience of JAK inhibitors in eyebrow regrowth for alopecia areata: A retrospective single-center study

    R. Ji, J. Huang, J. Jian, J. Cao, M. Li, T. Tian, X. Liang, J. Li, F. Liu, and W. Shi
    Journal of the American Academy of Dermatology. 2026. doi:10.1016/j.jaad.2026.01.017
  4. Proteomic profiling reveals distinct inflammatory and neurogenic endotypes in rosacea 2

    J. Huang, Y. Zhang, C. Yi, X. Xiao, D. Jian, W. Shi, F. Liu, Y. Huang, Z. Zhao, Y. Tang, M. Chen, Z. Deng, J. Li, Y. Zhang, and B. Wang
    Journal of the American Academy of Dermatology. 2026. doi:10.1016/j.jaad.2025.08.014
  5. A derivative of tanshinone alleviates rosacea-like skin inflammation by modulating the IL6/STAT3 signaling pathway in keratinocytes

    K. Xia, Z. Tan, X. Tang, M. Chen, Z. Deng, J. Li, H. Luo, J. Dong, Y. Zhu, S. Xu, and D. Jian
    Biochemical and biophysical research communications. 2026. doi:10.1016/j.bbrc.2025.153208
  6. Influence of serum lipids and polyunsaturated fatty acids on rosacea: Insights from prospective cohort studies

    R. Mao, Q. Yu, T. Zhang, X. Meng, and J. Li
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 2026. doi:10.1111/ddg.15978
  7. Real-World Efficacy of Ritlecitinib in Adolescent Patients With Alopecia Areata: A 36 Week Monocentric Real-Life Observational Study

    J. Huang, Z. Zhang, J. Jian, M. Li, R. Ji, T. Tian, X. Liang, Z. Zhao, Y. Tang, J. Li, F. Liu, and W. Shi
    Journal of cutaneous medicine and surgery. 2026. doi:10.1177/12034754261429965
  8. Sustaining treatment response in alopecia areata through tofacitinib dose tapering: A single-center retrospective study

    J. Huang, J. Jian, M. Li, R. Ji, T. Tian, X. Liang, Z. Zhao, Y. Tang, J. Li, F. Liu, and W. Shi
    Journal of the American Academy of Dermatology. 2026. doi:10.1016/j.jaad.2025.12.020
  9. Dynamics of Lipid Profile in Patients With Alopecia Areata Treated With Ritlecitinib: A Descriptive, Retrospective, Real-World Study

    M. Zhang, Y. Deng, J. Huang, M. Li, J. Jian, R. Ji, T. Tian, X. Liang, Z. Zhao, Y. Tang, J. Li, F. Liu, and W. Shi
    Journal of cutaneous medicine and surgery. 2026. doi:10.1177/12034754261431757
  10. Use of ritlecitinib in patients with alopecia areata refractory to tofacitinib or baricitinib: A single-center retrospective cohort study 1

    J. Huang, J. Jian, M. Li, R. Ji, T. Tian, X. Liang, Z. Zhao, Y. Tang, F. Liu, J. Li, and W. Shi
    Journal of the American Academy of Dermatology. 2026. doi:10.1016/j.jaad.2025.09.053
  11. Sequential immunotherapy with tofacitinib and low-dose IL-2 induces sustained remission in alopecia areata: a proof-of-concept monocentric study 1

    J. Huang, J. Jian, M. Li, R. Ji, X. Liang, Z. Zhao, Y. Tang, J. Li, F. Liu, and W. Shi
    QJM : monthly journal of the Association of Physicians. 2026. doi:10.1093/qjmed/hcaf221
  12. Response to comments on "Proteomic profiling reveals distinct inflammatory and neurogenic endotypes in rosacea"

    J. Huang, Y. Zhang, C. Yi, Y. Zhang, and B. Wang
    Journal of the American Academy of Dermatology. 2026. doi:10.1016/j.jaad.2026.01.058

2025

  1. HOXC10 Protects from Skin Aging by Targeting the FZD6/Wnt/β-Catenin Signaling Pathway

    Y. Zhong, Y. Guo, R. Mao, L. Zhou, F. Wang, X. Meng, X. Xiao, H. Yuan, Y. Zhang, Z. Deng, W. Shi, Q. Wang, H. Xie, Y. Zhang, and J. Li
    Research (Washington, D.C.). 2025. doi:10.34133/research.0976
  2. Arginine Metabolic Disruption Impairs Hair Regeneration via ROS-Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia 1

    S. Duan, G. Li, Y. Chu, J. Zhang, L. Yang, Y. Zhang, F. Liu, J. Li, M. Chen, B. Wang, Z. Zhao, W. Shi, Y. Zhang, G. Deng, X. Kuang, H. Xie, Y. Cheng, Z. Deng, J. Li, and Y. Tang
    Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2025. doi:10.1002/advs.202504579
  3. Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C 5

    T. Li, X. Li, X. Xiang, J. Huang, X. Shen, M. Wang, J. Jiang, S. Shao, Z. Li, T. Xie, D. Liu, Y. Zhao, R. Ma, W. Wu, W. Shi, C. Chuong, J. Li, and M. Lei
    Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2025. doi:10.1002/advs.202502436
  4. Downregulated TFPI2 Accelerates Skin Aging by Repressing the Cell Cycle through Phosphoinositide 3-Kinase/Protein Kinase B/CDC6 Pathway 4

    F. Wang, C. Yi, Y. Zhong, L. Zhou, X. Meng, R. Mao, Y. Guo, H. Xie, Y. Zhang, Y. Huang, and J. Li
    The Journal of investigative dermatology. 2025. doi:10.1016/j.jid.2024.11.028
  5. Keratin 6A promotes skin inflammation through JAK1-STAT3 activation in keratinocytes 8

    M. Chen, Y. Wang, M. Wang, S. Xu, Z. Tan, Y. Cai, X. Xiao, B. Wang, Z. Deng, and J. Li
    Journal of biomedical science. 2025. doi:10.1186/s12929-025-01143-9
  6. Novel Molecular Subtyping Revealed Molecular Pathways That Contribute to the Pathogenesis of Rosacea

    X. Hu, L. Liu, Y. Huang, Y. Zhang, H. Zhao, H. Zhao, Y. Guo, H. Xie, Z. Deng, M. Chen, and J. Li
    The Journal of dermatology. 2025. doi:10.1111/1346-8138.17798
  7. Linoleic acid improves rosacea through repairing mitochondrial damage in keratinocytes 2

    M. Wang, W. Xiao, T. Liu, Y. Zhu, M. Chen, Z. Tan, S. Xu, Z. Zhao, F. Liu, H. Xie, X. He, Z. Deng, and J. Li
    Life medicine. 2025. doi:10.1093/lifemedi/lnaf005
  8. Longevity Humans Have Youthful Erythrocyte Function and Metabolic Signatures 12

    F. Yu, C. Chen, W. Liu, Z. Zhao, Y. Fan, Z. Li, W. Huang, T. Xie, C. Luo, Z. Yao, Q. Guo, Z. Yang, J. Liu, Y. Zhang, R. E. Kellems, J. Xia, J. Li, and Y. Xia
    Aging cell. 2025. doi:10.1111/acel.14482
  9. Naturally-occurring carnosic acid as a promising therapeutic agent for skin inflammation via targeting STAT1 4

    A. Wu, Y. Wang, R. Mao, Z. Tan, S. Xu, J. Long, Q. Wang, Z. Zhao, H. Xie, Z. Deng, J. Li, and M. Chen
    Phytomedicine : international journal of phytotherapy and phytopharmacology. 2025. doi:10.1016/j.phymed.2025.156442
  10. 17β-Estradiol promotes LL37-induced rosacea-like skin inflammation via G protein-coupled estrogen receptor 30 2

    J. Tang, P. Chen, C. Huang, W. Wang, B. Wang, W. Shi, Y. Tang, Z. Deng, Y. Zhang, J. Li, and D. Jian
    Journal of dermatological science. 2025. doi:10.1016/j.jdermsci.2025.05.005
  11. Real-world efficacy of ritlecitinib in treating alopecia areata across various anatomical sites: Potential rapid response predictors 3

    J. Huang, J. Jian, M. Li, R. Ji, T. Tian, X. Liang, Z. Zhao, Y. Tang, F. Liu, J. Li, and W. Shi
    Journal of the American Academy of Dermatology. 2025. doi:10.1016/j.jaad.2025.07.008
  12. Targeting the STAT3/IL-36G signaling pathway can be a promising approach to treat rosacea 41

    X. Meng, Y. Zhong, X. Kuang, Y. Zhang, L. Yang, Y. Cai, F. Wang, F. He, H. Xie, B. Wang, and J. Li
    Journal of advanced research. 2025. doi:10.1016/j.jare.2024.06.013
  13. Dynamic tRNA Modification Landscapes Reveal METTL1 in fibroblasts as a Central Regulator of Aging

    Y. Zhu, X. Wang, Y. Li, W. Jiang, Z. Wu, S. Xu, Z. Tan, A. Wu, Y. Cai, Y. Yang, X. Xiao, X. Kuang, G. Deng, Y. Zhang, M. Chen, J. Li, Y. Zhang, and Z. Deng
    Science China Life Sciences. 2025. doi:10.1007/s11427-025-3287-6
  14. Oxidative stress mediated by the NOX2/ROS/NF-κB signaling axis is involved in rosacea 10

    Y. Wang, L. Long, M. Chen, and J. Li
    Archives of dermatological research. 2025. doi:10.1007/s00403-025-03898-5
  15. Correction: miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1

    H. Xie, Y. Liu, R. Du, B. Wang, M. Chen, Y. Zhang, Z. Deng, and J. Li
    Cell death & disease. 2025. doi:10.1038/s41419-025-08184-w
  16. Pd Icosahedral Nanoparticles Promote Skin Wound Healing by Enhancing SP1-HBEGF Axis-Mediated Keratinocytes Proliferation 2

    F. He, M. Li, H. Zhao, H. Zhao, X. Meng, Y. Zhang, Y. Tang, H. Huang, J. Li, H. Xie, and B. Wang
    International journal of nanomedicine. 2025. doi:10.2147/IJN.S499289
  17. Effectiveness and tolerability of ritlecitinib in children with alopecia areata: A case series 4

    J. Huang, J. Jian, M. Li, R. Ji, J. Li, and W. Shi
    Journal of the American Academy of Dermatology. 2025. doi:10.1016/j.jaad.2025.01.090
  18. Association of aging and the risk of late-onset psoriasis: Evidence from the UK Biobank cohort 1

    Z. Yang, F. Wang, T. Zhang, R. Mao, and J. Li
    Journal of the American Academy of Dermatology. 2025. doi:10.1016/j.jaad.2025.01.070
  19. Evaluating the Impact of Omega-3 Fatty Acids and Genetic Susceptibility on Atopic Dermatitis in Adults 5

    R. Mao, X. Meng, T. Zhang, F. Wang, Y. Zhong, and J. Li
    Molecular nutrition & food research. 2025. doi:10.1002/mnfr.70002

2024

  1. Probiotics suppress LL37 generated rosacea-like skin inflammation by modulating the TLR2/MyD88/NF-κB signaling pathway 19

    X. Qi, Y. Xiao, X. Zhang, Z. Zhu, H. Zhang, J. Wei, Z. Zhao, J. Li, and T. Chen
    Food & function. 2024. doi:10.1039/d4fo03083d
  2. Rosacea Core Domain Set for Clinical Trials and Practice: A Consensus Statement 4

    M. A. Dirr, A. Ahmed, D. I. Schlessinger, M. Haq, V. Shi, E. Koza, M. Ma, R. E. Christensen, S. A. Ibrahim, J. Schmitt, L. Johannsen, Y. Asai, H. E. Baldwin, E. Berardesca, B. Berman, A. C. Vieira, A. L. Chien, D. E. Cohen, J. Q. Del Rosso, J. Dosal, L. A. Drake, S. R. Feldman, A. B. Fleischer, A. Friedman, E. Graber, J. C. Harper, Y. R. Helfrich, G. B. Jemec, S. M. Johnson, R. Katta, P. Lio, L. E. Maier, G. Martin, A. R. Nagler, I. M. Neuhaus, M. Palamar, L. C. Parish, T. Rosen, S. P. Shumack, J. A. Solomon, E. A. Tanghetti, G. F. Webster, A. Weinkle, J. S. Weiss, E. J. Wladis, I. A. Maher, J. F. Sobanko, T. V. Cartee, B. A. Cahn, M. Alam, IMPROVED-COS Rosacea Working Group, B. Y. Kang, S. Iyengar, N. Anvery, E. Alpsoy, A. Bewley, C. Dessinioti, A. Egeberg, B. Engin, H. P. M. Gollnick, D. Ioannides, H. S. Kim, E. Lazaridou, J. Li, H. G. Lim, G. Micali, C. M. M. Oliveira, L. Noguera-Morel, A. Parodi, M. Reinholz, D. H. Suh, Q. Sun, E. J. Zuuren, U. Wollina, Y. Zhou, C. Zip, E. Poon, and R. Pearlman
    JAMA dermatology. 2024. doi:10.1001/jamadermatol.2024.0636
  3. Pyroptosis-related gene signature elicits immune response in rosacea 6

    X. Hu, S. Zheng, R. Mao, Q. Zhang, X. Wan, Y. Zhang, J. Li, R. Yang, and K. Xiong
    Experimental dermatology. 2024. doi:10.1111/exd.14812
  4. Hematological parameters as diagnostic biomarkers for patients with rosacea 2

    S. Liang, Y. Fang, Z. Zhao, B. Wang, Y. Huang, H. Xie, Y. Zhang, and J. Li
    The Journal of dermatology. 2024. doi:10.1111/1346-8138.17168
  5. Mouse model of a long-term rosacea-like skin inflammation 1

    X. Hu, Y. Chang, S. Zheng, J. Zhang, H. Zhao, Y. Guo, Y. Hao, T. Wang, Y. Liu, J. Feng, Y. Zhang, and J. Li
    Archives of dermatological research. 2024. doi:10.1007/s00403-024-03301-9
  6. Effectiveness and safety of generic tofacitinib in alopecia areata: is the generic a cost-effective option? A retrospective study 2

    J. Jian, M. Li, P. Qian, J. Li, Y. Tang, F. Liu, Z. Zhao, J. Huang, and W. Shi
    Archives of dermatological research. 2024. doi:10.1007/s00403-024-02879-4
  7. Single-cell transcriptomics reveals aberrant skin-resident cell populations and identifies fibroblasts as a determinant in rosacea 16

    M. Chen, L. Yang, P. Zhou, S. Jin, Z. Wu, Z. Tan, W. Xiao, S. Xu, Y. Zhu, M. Wang, D. Jian, F. Liu, Y. Tang, Z. Zhao, Y. Huang, W. Shi, H. Xie, Q. Nie, B. Wang, Z. Deng, and J. Li
    Nature communications. 2024. doi:10.1038/s41467-024-52946-7
  8. High-sensitive sensory neurons exacerbate rosacea-like dermatitis in mice by activating γδ T cells directly 16

    Y. Zhang, T. Li, H. Zhao, X. Xiao, X. Hu, B. Wang, Y. Huang, Z. Yin, Y. Zhong, Y. Li, and J. Li
    Nature communications. 2024. doi:10.1038/s41467-024-50970-1
  9. Downregulated SPESP1-driven fibroblast senescence decreases wound healing in aged mice 6

    Y. Zhong, L. Zhou, Y. Guo, F. Wang, F. He, Y. Cheng, X. Meng, H. Xie, Y. Zhang, and J. Li
    Clinical and translational medicine. 2024. doi:10.1002/ctm2.1660
  10. SERPINB3/B4 Is Increased in Psoriasis and Rosacea Lesions and Has Proinflammatory Effects in Mouse Models of these Diseases 5

    W. Xiao, K. Sha, M. Wang, Z. Tan, Y. Wang, S. Xu, Z. Zhao, Q. Wang, H. Xie, M. Chen, Z. Deng, and J. Li
    The Journal of investigative dermatology. 2024. doi:10.1016/j.jid.2024.04.011
  11. WTAP Mediated N6-methyladenosine RNA Modification of ELF3 Drives Cellular Senescence by Upregulating IRF8 16

    L. Zhou, Y. Zhong, F. Wang, Y. Guo, R. Mao, H. Xie, Y. Zhang, and J. Li
    International journal of biological sciences. 2024. doi:10.7150/ijbs.90459
  12. Twin defect-rich Pt ultrathin nanowire nanozymes alleviate inflammatory skin diseases by scavenging reactive oxygen species 27

    H. Zhao, H. Zhao, M. Li, Y. Tang, X. Xiao, Y. Cai, F. He, H. Huang, Y. Zhang, and J. Li
    Redox biology. 2024. doi:10.1016/j.redox.2024.103055
  13. Skin Aging Research Enters a New Era in China 2

    M. Chen, J. Li, Y. Ding, and C. Zhang
    The Journal of investigative dermatology. 2024. doi:10.1016/j.jid.2024.03.025
  14. Integrated Omics Reveal the Molecular Characterization and Pathogenic Mechanism of Rosacea 11

    Y. Zhang, Y. Huang, B. Wang, W. Shi, X. Hu, Y. Wang, Y. Guo, H. Xie, W. Xiao, and J. Li
    The Journal of investigative dermatology. 2024. doi:10.1016/j.jid.2023.05.028
  15. Quercetin attenuates inflammation in rosacea by directly targeting p65 and ICAM-1 8

    X. Meng, Y. Li, F. Wang, T. Li, B. Wang, Q. Wang, J. Long, H. Xie, Y. Zhang, and J. Li
    Life sciences. 2024. doi:10.1016/j.lfs.2024.122675
  16. Skin-permeable gold nanoparticles with modifications azelamide monoethanolamine ameliorate inflammatory skin diseases 9

    H. Zhao, H. Zhao, Y. Tang, M. Li, Y. Cai, X. Xiao, F. He, H. Huang, Y. Zhang, and J. Li
    Biomarker research. 2024. doi:10.1186/s40364-024-00663-0
  17. Integrated bioinformatics analysis and experimental validation identifies CPE as a potential biomarker and therapeutic target for skin aging 1

    X. Peng, Y. Zhong, R. Mao, F. He, Y. Cheng, M. Chen, L. Zhou, H. Xie, J. Li, and Y. Zhang
    Experimental dermatology. 2024. doi:10.1111/exd.15120
  18. Clinical characteristics of the well-defined upper eyelid vascular network pattern in patients with rosacea 4

    Y. Peng, B. Wang, M. Mao, J. Li, W. Shi, H. Zhao, Z. Huang, Z. Zhao, C. Huang, and D. Jian
    International journal of dermatology. 2024. doi:10.1111/ijd.16946
  19. Correction: A Novel Convolutional Neural Network for the Diagnosis and Classification of Rosacea: Usability Study

    Z. Zhao, C. Wu, S. Zhang, F. He, F. Liu, B. Wang, Y. Huang, W. Shi, D. Jian, H. Xie, C. Yeh, and J. Li
    JMIR medical informatics. 2024. doi:10.2196/57654
  20. Thermal-Responsive Gel-Based Overheat Limiter Enabled Intelligent Photothermal Therapy 18

    Y. Chu, Q. Wang, S. Lyu, B. Yuan, J. Huang, J. Li, and Y. Wang
    Small (Weinheim an der Bergstrasse, Germany). 2024. doi:10.1002/smll.202312140
  21. Dupliumab therapy for alopecia areata: a case series and review of the literature 15

    J. Huang, J. Jian, T. Li, M. Li, K. Luo, S. Deng, Y. Tang, F. Liu, Z. Zhao, W. Shi, and J. Li
    The Journal of dermatological treatment. 2024. doi:10.1080/09546634.2024.2312245

2023

  1. GBP5 exacerbates rosacea-like skin inflammation by skewing macrophage polarization towards M1 phenotype through the NF-κB signalling pathway 70

    L. Zhou, H. Zhao, H. Zhao, X. Meng, Z. Zhao, H. Xie, J. Li, Y. Tang, and Y. Zhang
    Journal of the European Academy of Dermatology and Venereology : JEADV. 2023. doi:10.1111/jdv.18725
  2. Efficacy and safety of antibiotic agents in the treatment of rosacea: a systemic network meta-analysis 17

    W. Xiao, M. Chen, B. Wang, Y. Huang, Z. Zhao, Z. Deng, H. Xie, J. Li, and Y. Tang
    Frontiers in pharmacology. 2023. doi:10.3389/fphar.2023.1169916
  3. Drug Survival and Long-term Outcome of Tofacitinib in Patients with Alopecia Areata: A Retrospective Study 12

    J. Huang, S. Deng, J. Li, Y. Tang, F. Liu, Y. Liu, S. Rao, and W. Shi
    Acta dermato-venereologica. 2023. doi:10.2340/actadv.v103.13475
  4. TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea 13

    Y. Huang, D. Liu, M. Chen, S. Xu, Q. Peng, Y. Zhu, J. Long, T. Liu, Z. Deng, H. Xie, J. Li, F. Liu, and W. Xiao
  5. Associations of adherence to Mediterranean-like diet pattern with incident rosacea: A prospective cohort study of government employees in China 10

    P. Chen, Z. Yang, Z. Fan, B. Wang, Y. Tang, Y. Xiao, X. Chen, D. Luo, S. Xiao, J. Li, H. Xie, and M. Shen
    Frontiers in nutrition. 2023. doi:10.3389/fnut.2023.1092781
  6. Associations of polysocial risk score with incident rosacea: a prospective cohort study of government employees in China 12

    P. Chen, Z. Yang, Z. Fan, B. Wang, Y. Tang, Y. Xiao, X. Chen, D. Luo, S. Xiao, J. Li, and M. Shen
    Frontiers in public health. 2023. doi:10.3389/fpubh.2023.1096687
  7. Whole genome sequencing identifies genetic variants associated with neurogenic inflammation in rosacea 41

    Z. Deng, M. Chen, Z. Zhao, W. Xiao, T. Liu, Q. Peng, Z. Wu, S. Xu, W. Shi, D. Jian, B. Wang, F. Liu, Y. Tang, Y. Huang, Y. Zhang, Q. Wang, L. Sun, H. Xie, G. Zhang, and J. Li
    Nature communications. 2023. doi:10.1038/s41467-023-39761-2
  8. The Aging Biomarker Consortium represents a new era for aging research in China 55

    J. Ren, M. Song, W. Zhang, J. Cai, F. Cao, Z. Cao, P. Chan, C. Chen, G. Chen, H. Chen, J. Chen, X. Chen, W. Ci, B. Ding, Q. Ding, F. Gao, S. Gao, J. J. Han, Q. He, K. Huang, Z. Ju, Q. Kong, J. Li, J. Li, J. Li, X. Li, B. Liu, F. Liu, J. Liu, L. Liu, Q. Liu, Q. Liu, X. Liu, Y. Liu, X. Luo, S. Ma, X. Ma, Z. Mao, J. Nie, Y. Peng, J. Qu, R. Ren, W. Song, Z. Songyang, L. Sun, Y. E. Sun, Y. Sun, M. Tian, X. Tian, Y. Tian, J. Wang, S. Wang, S. Wang, W. Wang, X. Wang, X. Wang, Y. Wang, Y. Wang, C. C. L. Wong, A. P. Xiang, Y. Xiao, Z. Xiao, Z. Xie, W. Xiong, D. Xu, Z. Yang, J. Ye, W. Yu, R. Yue, C. Zhang, H. Zhang, L. Zhang, X. Zhang, Y. Zhang, Y. Zhang, Z. Zhang, T. Zhao, Y. Zhao, Z. Zhou, D. Zhu, W. Zou, G. Pei, and G. Liu
    Nature medicine. 2023. doi:10.1038/s41591-023-02444-y
  9. Paroxetine is an effective treatment for refractory erythema of rosacea: Primary results from the Prospective Rosacea Refractory Erythema Randomized Clinical Trial 35

    B. Wang, Y. Huang, Y. Tang, Z. Zhao, W. Shi, D. Jian, F. Liu, Q. Gao, P. Wang, J. Yang, L. Li, H. Xie, and J. Li
    Journal of the American Academy of Dermatology. 2023. doi:10.1016/j.jaad.2023.01.044
  10. Targeting Aquaporin-3 Attenuates Skin Inflammation in Rosacea 16

    M. Chen, Q. Peng, Z. Tan, S. Xu, Y. Wang, A. Wu, W. Xiao, Q. Wang, H. Xie, J. Li, W. Shi, and Z. Deng
    International journal of biological sciences. 2023. doi:10.7150/ijbs.86207
  11. Granulomatous rosacea in Chinese patients: Clinical-histopathological analysis and pathogenesis exploration 7

    Y. Jiang, Y. Huang, G. Ma, T. Liu, Q. Li, H. Wu, and J. Li
    The Journal of dermatology. 2023. doi:10.1111/1346-8138.16767
  12. Longevity-Associated Transcription Factor ATF7 Promotes Healthspan by Suppressing Cellular Senescence and Systematic Inflammation 10

    Y. Huang, M. Ge, Y. Li, J. Li, Q. Yu, F. Xiao, H. Ao, L. Yang, J. Li, Y. He, and Q. Kong
    Aging and disease. 2023. doi:10.14336/AD.2022.1217
  13. EGCG identified as an autophagy inducer for rosacea therapy 9

    L. Zhou, Y. Zhong, Y. Wang, Z. Deng, Y. Huang, Q. Wang, H. Xie, Y. Zhang, and J. Li
    Frontiers in pharmacology. 2023. doi:10.3389/fphar.2023.1092473

2022

  1. Current research and clinical trends in rosacea pathogenesis 33

    X. Hu, Z. Li, D. Zhang, Y. Yang, S. Zheng, Q. Zhang, X. Wan, J. Li, R. Yang, and K. Xiong
  2. Lithocholic acid promotes rosacea-like skin inflammation via G protein-coupled bile acid receptor 1 15

    W. Xiao, M. Chen, Q. Peng, K. Sha, T. Liu, J. Xia, H. Xie, J. Li, S. Xu, and Z. Deng
    Biochimica et biophysica acta. Molecular basis of disease. 2022. doi:10.1016/j.bbadis.2022.166563
  3. Regulation and dysregulation of hair regeneration: aiming for clinical application 10

    Z. Yue, F. Yang, J. Zhang, J. Li, and C. Chuong
    Cell regeneration (London, England). 2022. doi:10.1186/s13619-022-00122-x
  4. Aberrant amino acid metabolism promotes neurovascular reactivity in rosacea 24

    T. Liu, W. Xiao, M. Chen, R. Mao, X. San, Q. Peng, Z. Zhao, Q. Wang, H. Xie, Z. Deng, and J. Li
    JCI insight. 2022. doi:10.1172/jci.insight.161870
  5. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state 80

    Y. Liu, C. F. Guerrero-Juarez, F. Xiao, N. U. Shettigar, R. Ramos, C. Kuan, Y. Lin, L. Jesus Martinez Lomeli, J. M. Park, J. W. Oh, R. Liu, S. Lin, M. Tartaglia, R. Yang, Z. Yu, Q. Nie, J. Li, and M. V. Plikus
    Developmental cell. 2022. doi:10.1016/j.devcel.2022.06.005
  6. ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity 60

    F. Xiao, Q. Yu, Z. Deng, K. Yang, Y. Ye, M. Ge, D. Yan, H. Wang, X. Chen, L. Yang, B. Yang, R. Lin, W. Zhang, X. Yang, L. Dong, Y. He, J. Zhou, W. Cai, J. Li, and Q. Kong
    Science advances. 2022. doi:10.1126/sciadv.abf2017
  7. Aging-Conferred SIRT7 Decline Inhibits Rosacea-Like Skin Inflammation by Modulating Toll-Like Receptor 2‒NF-κB Signaling 28

    G. Li, X. Tang, S. Zhang, Z. Deng, B. Wang, W. Shi, H. Xie, B. Liu, and J. Li
    The Journal of investigative dermatology. 2022. doi:10.1016/j.jid.2022.03.026
  8. Nav1.8 in keratinocytes contributes to ROS-mediated inflammation in inflammatory skin diseases 59

    Y. Zhang, Y. Li, L. Zhou, X. Yuan, Y. Wang, Q. Deng, Z. Deng, S. Xu, Q. Wang, H. Xie, and J. Li
    Redox biology. 2022. doi:10.1016/j.redox.2022.102427
  9. Androgen Receptor-Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia 85

    Z. Deng, M. Chen, F. Liu, Y. Wang, S. Xu, K. Sha, Q. Peng, Z. Wu, W. Xiao, T. Liu, H. Xie, and J. Li
    The Journal of investigative dermatology. 2022. doi:10.1016/j.jid.2022.01.003
  10. N2-Polarized Neutrophils Reduce Inflammation in Rosacea by Regulating Vascular Factors and Proliferation of CD4+ T Cells 35

    Z. Zhao, T. Liu, Y. Liang, W. Cui, D. Li, G. Zhang, Z. Deng, M. Chen, K. Sha, W. Xiao, H. Xie, and J. Li
    The Journal of investigative dermatology. 2022. doi:10.1016/j.jid.2021.12.009
  11. Autophagy induction regulates aquaporin 3-mediated skin fibroblast ageing 30

    H. Xie, L. Zhou, F. Liu, J. Long, S. Yan, Y. Xie, X. Hu, and J. Li
    The British journal of dermatology. 2022. doi:10.1111/bjd.20662
  12. Health Related Quality of Life of Rosacea Patients in China Assessed by Dermatology Life Quality Index and Willingness to Pay 13

    Y. Huang, S. Yan, H. Xie, B. Wang, Z. Zhao, Y. Huang, and J. Li
    Patient preference and adherence. 2022. doi:10.2147/PPA.S345258
  13. A novel multi-layer perceptron model for assessing the diagnostic value of non-invasive imaging instruments for rosacea 9

    Y. Huang, J. He, S. Zhang, Y. Tang, B. Wang, D. Jian, H. Xie, J. Li, F. Chen, and Z. Zhao
  14. Neuroimmune Interaction: A Widespread Mutual Regulation and the Weapons for Barrier Organs 17

    Y. Zhu, S. Duan, M. Wang, Z. Deng, and J. Li
    Frontiers in cell and developmental biology. 2022. doi:10.3389/fcell.2022.906755
  15. A rapidly progressing, painful ulcer at a surgical wound site 1

    S. Rao, Y. Tang, J. Li, and W. Shi
    BMJ (Clinical research ed.). 2022. doi:10.1136/bmj-2021-068211
  16. Mammary Paget Disease With Melanocytic Proliferation Mimicking Malignant Melanoma in situ: A Case Report 11

    S. Rao, A. Wang, W. Liu, H. Yin, J. Li, L. S. Tsang, Y. Wu, and W. Shi
    Frontiers in medicine. 2022. doi:10.3389/fmed.2022.839954
  17. Increased serum levels of CCL3, CXCL8, CXCL9, and CXCL10 in rosacea patients and their correlation with disease severity 14

    T. Liu, J. Li, Z. Deng, M. Chen, K. Sha, W. Xiao, H. Xie, and Z. Zhao
    The Journal of dermatology. 2022. doi:10.1111/1346-8138.16329

2021

  1. 中国玫瑰痤疮诊疗指南(2021版) 8

    中华医学会皮肤性病学分会玫瑰痤疮研究中心 and 中国医师协会皮肤科医师分会玫瑰痤疮专业委员会
    中华皮肤科杂志. 2021. doi:10.35541/cjd.20201078
  2. A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea 103

    Z. Deng, M. Chen, Y. Liu, S. Xu, Y. Ouyang, W. Shi, D. Jian, B. Wang, F. Liu, J. Li, Q. Shi, Q. Peng, K. Sha, W. Xiao, T. Liu, Y. Zhang, H. Zhang, Q. Wang, L. Sun, H. Xie, and J. Li
    EMBO molecular medicine. 2021. doi:10.15252/emmm.202013560
  3. Aspirin alleviates skin inflammation and angiogenesis in rosacea 21

    Z. Deng, S. Xu, Q. Peng, K. Sha, W. Xiao, T. Liu, Y. Zhang, B. Wang, H. Xie, M. Chen, and J. Li
    International immunopharmacology. 2021. doi:10.1016/j.intimp.2021.107558
  4. A Novel Convolutional Neural Network for the Diagnosis and Classification of Rosacea: Usability Study 54

    Z. Zhao, C. Wu, S. Zhang, F. He, F. Liu, B. Wang, Y. Huang, W. Shi, D. Jian, H. Xie, C. Yeh, and J. Li
    JMIR medical informatics. 2021. doi:10.2196/23415
  5. Keratinocyte-Immune Cell Crosstalk in a STAT1-Mediated Pathway: Novel Insights Into Rosacea Pathogenesis 49

    Z. Deng, F. Liu, M. Chen, C. Huang, W. Xiao, S. Gao, D. Jian, Y. Ouyang, S. Xu, J. Li, Q. Shi, H. Xie, G. Zhang, and J. Li
    Frontiers in immunology. 2021. doi:10.3389/fimmu.2021.674871
  6. Exploring metformin as a candidate drug for rosacea through network pharmacology and experimental validation 28

    Y. Li, L. Yang, Y. Wang, Z. Deng, S. Xu, H. Xie, Y. Zhang, and J. Li
    Pharmacological research. 2021. doi:10.1016/j.phrs.2021.105971
  7. mTORC1-Mediated Angiogenesis is Required for the Development of Rosacea 20

    Q. Peng, K. Sha, Y. Liu, M. Chen, S. Xu, H. Xie, Z. Deng, and J. Li
    Frontiers in cell and developmental biology. 2021. doi:10.3389/fcell.2021.751785
  8. Excessive cleansing: an underestimating risk factor of rosacea in Chinese population 20

    G. Li, B. Wang, Z. Zhao, W. Shi, D. Jian, H. Xie, Y. Huang, and J. Li
    Archives of dermatological research. 2021. doi:10.1007/s00403-020-02095-w
  9. Willingness-to-Pay and Benefit-Cost Analysis of Botulinum Toxin for the Treatment of Rosacea in China: Findings from a Web-Based Survey 4

    X. Yang, Y. Ouyang, Y. Deng, Y. Xiao, Y. Tang, D. Jian, J. Li, H. Xie, and Y. Huang
    Patient preference and adherence. 2021. doi:10.2147/PPA.S311322
  10. Clinical Features and Risk Factors for Nasal Rosacea: A Hospital-Based Retrospective Study 3

    A. Wu, F. Liu, H. Xie, Z. Zhao, Y. Tang, Y. Huang, D. Jian, W. Shi, B. Wang, and J. Li
    Dermatology and therapy. 2021. doi:10.1007/s13555-021-00605-w
  11. Efficacy and safety of hydroxychloroquine for treatment of patients with rosacea: A multicenter, randomized, double-blind, double-dummy, pilot study 38

    B. Wang, X. Yuan, X. Huang, Y. Tang, Z. Zhao, B. Yang, B. Yang, Y. Zheng, C. Yuan, H. Xie, and J. Li
    Journal of the American Academy of Dermatology. 2021. doi:10.1016/j.jaad.2020.05.050
  12. Relationship Between Tea Drinking Behaviour and Rosacea: A Clinical Case-control Study 1

    B. Wang, B. Yan, Z. Zhao, Y. Tang, Y. Huang, D. Jian, W. Shi, H. Xie, Y. Wang, and J. Li
    Acta dermato-venereologica. 2021. doi:10.2340/00015555-3849
  13. Bioinformatics and Network Pharmacology Identify the Therapeutic Role and Potential Mechanism of Melatonin in AD and Rosacea 86

    H. Zhang, Y. Zhang, Y. Li, Y. Wang, S. Yan, S. Xu, Z. Deng, X. Yang, H. Xie, and J. Li
    Frontiers in immunology. 2021. doi:10.3389/fimmu.2021.756550
  14. Reply

    Q. Chen, Y. Tang, and J. Li
    Journal of the American Academy of Dermatology. 2021. doi:10.1016/j.jaad.2021.01.091
  15. Relationship between the exercise and severity of androgenic alopecia

    Y. Jiang, Q. Shi, Y. Huang, J. Li, H. Xie, and F. Liu
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2021. doi:10.11817/j.issn.1672-7347.2021.200801

2020

  1. Epidemiological features of rosacea in Changsha, China: A population-based, cross-sectional study 61

    J. Li, B. Wang, Y. Deng, W. Shi, D. Jian, F. Liu, Y. Huang, Y. Tang, Z. Zhao, X. Huang, J. Li, and H. Xie
    The Journal of dermatology. 2020. doi:10.1111/1346-8138.15301
  2. Skincare Habits and Rosacea in 3,439 Chinese Adolescents: A University-based Cross-sectional Study 17

    Z. Zuo, B. Wang, M. Shen, H. Xie, J. Li, X. Chen, and Y. Zhang
    Acta dermato-venereologica. 2020. doi:10.2340/00015555-3442
  3. Willingness-to-Pay and Benefit-Cost Analysis of IPL for Rosacea Treatment: A Cross-Sectional Study in China 8

    Q. Deng, S. Zhang, Y. Deng, F. Liu, W. Shi, H. Xie, Y. Xiao, Y. Huang, and J. Li
    Patient preference and adherence. 2020. doi:10.2147/PPA.S271859
  4. Prevalence, clinical characteristics and health-related quality of life of rosacea in Chinese adolescents: a population-based study 13

    Q. Chen, Y. Tang, X. Shi, X. Yang, S. Shan, X. Wang, Y. Xiao, X. Chen, M. Shen, and J. Li
    Journal of the European Academy of Dermatology and Venereology : JEADV. 2020. doi:10.1111/jdv.16576
  5. ADAMDEC1 promotes skin inflammation in rosacea via modulating the polarization of M1 macrophages 55

    T. Liu, Z. Deng, H. Xie, M. Chen, S. Xu, Q. Peng, K. Sha, W. Xiao, Z. Zhao, and J. Li
    Biochemical and biophysical research communications. 2020. doi:10.1016/j.bbrc.2019.10.073
  6. Hair regeneration after epidermal peeling 1

    Z. Wang, J. Luo, and J. Li
    European journal of dermatology : EJD. 2020. doi:10.1684/ejd.2020.3744
  7. Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1 6

    B. Wang, S. Yan, Y. Yi, Y. Huang, Z. Deng, Y. Zhang, Q. Zheng, H. Xie, and J. Li
    Frontiers in cell and developmental biology. 2020. doi:10.3389/fcell.2020.00691
  8. A Negative Feedback Loop in Ultraviolet A-Induced Senescence in Human Dermal Fibroblasts Formed by SPCA1 and MAPK 12

    H. Xie, X. Xiao, Y. Yi, M. Deng, P. Li, D. Jian, Z. Deng, and J. Li
    Frontiers in cell and developmental biology. 2020. doi:10.3389/fcell.2020.597993
  9. Hydroxychloroquine is a novel therapeutic approach for rosacea 40

    J. Li, X. Yuan, Y. Tang, B. Wang, Z. Deng, Y. Huang, F. Liu, Z. Zhao, and Y. Zhang
    International immunopharmacology. 2020. doi:10.1016/j.intimp.2019.106178
  10. Identification and verification of EOMEs regulated network in Alopecia areata 12

    X. Yuan, Y. Tang, Z. Zhao, F. Liu, W. Shi, Y. Zhang, and J. Li
    International immunopharmacology. 2020. doi:10.1016/j.intimp.2020.106544
  11. Identification and verification immune-related regulatory network in acne 7

    Y. Xin, S. Zhang, Z. Deng, D. Zeng, J. Li, and Y. Zhang
    International immunopharmacology. 2020. doi:10.1016/j.intimp.2020.107083
  12. Association between rosacea and cardiometabolic disease: A systematic review and meta-analysis 62

    Q. Chen, X. Shi, Y. Tang, B. Wang, H. Xie, W. Shi, and J. Li
    Journal of the American Academy of Dermatology. 2020. doi:10.1016/j.jaad.2020.04.113
  13. Haplopelma hainanum venom induces inflammatory skin lesions 1

    Z. Deng, Y. Wang, W. Shi, L. Zhou, S. Xu, J. Li, and Y. Zhang
    PeerJ. 2020. doi:10.7717/peerj.8264
  14. Relationship between rosacea and sleep 40

    Z. Wang, H. Xie, Y. Gong, Y. Ouyang, F. Deng, Y. Tang, and J. Li
    The Journal of dermatology. 2020. doi:10.1111/1346-8138.15339
  15. Relationship between the incidence of rosacea and drinking or smoking in China

    Y. Wang, Z. Zhao, F. Liu, H. Xie, J. Li, and B. Wang
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2020. doi:10.11817/j.issn.1672-7347.2020.180759